| FDG/PET and spiral CT image fusion for medistinal lymph node assessment of non-small cell lung cancer patients. | |
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MedLine Citation:
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PMID: 10597015 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: To assess the potential usefulness of 18F-FDG/PET and spiral-CT images concurrent assessment and coregistration in staging mediastinal lymph node involvement in patients with non small cell lung cancer. METHODS: 28 patients waiting to undergo surgical treatment underwent spiral-CT and PET examinations on the same day. The results of the two studies were interpreted separately, together (CT&PET) and following their fusion in a single image (CT+PET). Results of spiral-CT, PET, CT&PET and CT+PET were assessed with respect to the histological diagnosis. RESULTS: A correct assessment of mediastinal lymph nodes was achieved by spiral-CT in 21 of the 28 patients, in 22 of the 28 patients by PET, in 24 patients by CT&PET and in 25 patients by CT+PET. CONCLUSIONS: CT+PET is more accurate than spiral-CT and PET alone in staging mediastinal lymph node involvement in lung cancer patients, with possible implications for their prognosis and therapy. |
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Authors:
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P Magnani; A Carretta; G Rizzo; F Fazio; A Vanzulli; G Lucignani; P Zannini; C Messa; C Landoni; M C Gilardi; A Del Maschio |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of cardiovascular surgery Volume: 40 ISSN: 0021-9509 ISO Abbreviation: J Cardiovasc Surg (Torino) Publication Date: 1999 Oct |
Date Detail:
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Created Date: 1999-12-27 Completed Date: 1999-12-27 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0066127 Medline TA: J Cardiovasc Surg (Torino) Country: ITALY |
Other Details:
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Languages: eng Pagination: 741-8 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, INB-CNR, Institute H.S. Raffaele, University of Milan, Milano, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Carcinoma, Non-Small-Cell Lung / diagnosis* Diagnosis, Differential Female Fluorodeoxyglucose F18 / diagnostic use* Humans Lung Neoplasms / diagnosis* Lymph Nodes* / pathology, radiography, radionuclide imaging Lymphatic Metastasis / pathology, radiography, radionuclide imaging Male Mediastinum Middle Aged Neoplasm Staging Observer Variation Prognosis Reproducibility of Results Sensitivity and Specificity Tomography, Emission-Computed* / methods Tomography, X-Ray Computed* |
| Chemical | |
Reg. No./Substance:
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63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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