| The spectrum of neuromyelitis optica: a case of NMO with extensive brain stem involvement. | |
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MedLine Citation:
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PMID: 17427272 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Neuromyelitis optica (NMO), regarded as a distinct clinical entity from multiple sclerosis (MS), is generally characterized by demyelinating lesions involving optic nerves and spinal cord with sparing of the brain. We report a case with initial clinical, radiological and serological features consistent with NMO, but with concomitant extensively clinical and radiological involvement of the brain stem. Although there are well defined criteria for NMO that restricts the lesions to optic nerves and spinal cord, the case presented here and the review of literature support the idea that NMO may present as a spectrum of clinical and radiological entities rather than the confining clinical criteria that has been hitherto applied. |
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Authors:
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Martina Vendrame; S Ausim Azizi |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Neurological research Volume: 29 ISSN: 0161-6412 ISO Abbreviation: Neurol. Res. Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2007-04-11 Completed Date: 2007-05-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7905298 Medline TA: Neurol Res Country: England |
Other Details:
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Languages: eng Pagination: 32-5 Citation Subset: IM |
Affiliation:
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Department of Neurology, 558 Parkinson Pavilion, 3401 North Broad Street Temple University, School of Medicine, Philadelphia, PA 19140, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies
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blood Autonomic Nervous System Diseases / etiology, physiopathology Biological Markers / blood Brain Stem / pathology*, physiopathology Cerebrospinal Fluid / cytology Diagnosis, Differential Disease Progression Female Humans Immunoglobulins, Intravenous / therapeutic use Leukocytosis / cerebrospinal fluid Magnetic Resonance Imaging Middle Aged Motor Neurons / pathology Nerve Fibers, Myelinated / pathology Neural Pathways / pathology Neuromyelitis Optica / blood, cerebrospinal fluid, diagnosis* Plasmapheresis Spinal Cord / pathology, physiopathology Steroids / therapeutic use Treatment Failure |
| Chemical | |
Reg. No./Substance:
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0/Antibodies; 0/Biological Markers; 0/Immunoglobulins, Intravenous; 0/Steroids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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