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The spectra, symptom profiles and overlap of Rome III functional gastrointestinal disorders in a tertiary center in South China.
MedLine Citation:
PMID:  25102919     Owner:  NLM     Status:  Publisher    
OBJECTIVE: Most of previous studies exploring the overlap of functional gastrointestinal disorders (FGIDs) only focused on overlap between functional dyspepsia (FD) and irritable bowel syndrome (IBS). Furthermore, there are no report about the spectra and overlap for the entire FGIDs in China. In this study, we sought to explore the spectra, symptom profiles and overlap for entire FGIDs using the validated Chinese version of Rome III questionnaire.
METHODS: The consecutive new FGIDs patients presenting to our gastroenterology out-patient clinic between 10(th) May and 10(th) September 2012 were recruited. The patients eligible for the inclusion criteria were asked to complete the questionnaire. FGIDs were coded according to the scoring algorithm for the Rome III integrative questionnaire.
RESULTS: Among 350 eligible patients, 302 (86.3%) patients returned the completed questionnaires. A total of six major domains including 17 disorders in Rome III classification system were diagnosed. The four most prevalent FGIDs were FD (54.6%), IBS (40.7%), unspecified functional bowel disorder (13.9%) and functional constipation (12.6%). The three most prevalent symptoms for FGIDs were abdominal pain (66.2%), loose stool (58.3%) and bloating/distension (56.3%). Of these 302 patients with FGIDs, 152 (50.3%) patients had overlapped 1 to 5 FGIDs. Only functional bloating had no overlap. There were 6 patients overlapping with another 5 FGIDs simultaneously. Sixty three patients had FD-IBS overlapping.
CONCLUSIONS: This study provided the detailed spectra and symptom profiles for entire FGIDs. The overlap among FGIDs was common in China.
Li Shou Xiong; Quan Shi; Xiao Rong Gong; Yi Cui; Min Hu Chen
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-8
Journal Detail:
Title:  Journal of digestive diseases     Volume:  -     ISSN:  1751-2980     ISO Abbreviation:  J Dig Dis     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-8-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101302699     Medline TA:  J Dig Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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This article is protected by copyright. All rights reserved.
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