| On the source of uterine 'luminal fluid' proteins in the mouse. | |
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MedLine Citation:
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PMID: 6726690 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Examination by light-, transmission electron- and scanning electron-microscopy showed that flushing the lumen of the mouse uterus with small volumes of fluid damaged the endometrium by rupturing and removing luminal epithelial cells, splitting the epithelial basement membrane and connective tissue stroma, and rupturing and leaching stromal cells and blood vessels. The damage increased with increasing progestation of the uterus and between Days 4 and 5 of pregnancy. I conclude that many so-called 'luminal fluid' proteins originate from luminal and stromal cells, intercellular fluid and blood and that apparent changes in luminal fluid protein content during early pregnancy may largely reflect alterations in the extent and type of damage produced by flushing, as a consequence of changes in the physical state of the uterus induced by hormones and the presence of blastocysts. |
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Authors:
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L Martin |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of reproduction and fertility Volume: 71 ISSN: 0022-4251 ISO Abbreviation: J. Reprod. Fertil. Publication Date: 1984 May |
Date Detail:
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Created Date: 1984-06-22 Completed Date: 1984-06-22 Revised Date: 2004-12-03 |
Medline Journal Info:
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Nlm Unique ID: 0376367 Medline TA: J Reprod Fertil Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 73-80 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Castration Endometrium / ultrastructure Epithelium / metabolism, ultrastructure Estradiol / pharmacology Female Glycoproteins* Mice Microscopy, Electron Microscopy, Electron, Scanning Pregnancy Progesterone / pharmacology Proteins / metabolism* Serpins* Uterus / drug effects, metabolism*, ultrastructure |
| Chemical | |
Reg. No./Substance:
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0/Glycoproteins; 0/Proteins; 0/Serpins; 0/uterine luminal fluid proteins; 50-28-2/Estradiol; 57-83-0/Progesterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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