Document Detail

The source of error in the estimation of intertwin birth weight discordance.
MedLine Citation:
PMID:  20707628     Owner:  NLM     Status:  In-Process    
OBJECTIVE: to assess the accuracy of paired estimated fetal weights (EFWs) to predict three levels of twin birth weight discordance (>15%, >20% and >25%).
METHOD: a cohort of twin pairs underwent ultrasound examinations within 2 weeks from birth. We calculated the frequency of under- and overestimation of the actual birth weight (< or >10%, respectively) in the entire cohort as well in the subset of mono- and dichorionic pairs.
RESULTS: discordance was largely underestimated (observed 10.4 ± 0.8% compared to actual 19.2 ± 1.1%, P=0.001) because the larger twin was more frequently underestimated [30.6 vs. 17.7%, odds ratio (OR) 2.0, 95% confidence interval (CI) 1.1, 3.9 in the entire cohort, and 34.2 vs. 13.1%, OR 3.4, 95% CI 1.4, 8.4 in the dichorionic pairs]. Overall, the specificity for detecting the three levels of discordance was adequate (91.5-94.2%) but the sensitivity was poor (11.1-17.8%) and tended to decrease with increasing discordance level.
CONCLUSION: the poor ability of paired EFWs to diagnose birth weight discordance results from underestimation of the larger twin.
Maria Augusta Reberdao; Luisa Martins; Mariana Torgal; Rui Viana; Tatiana Seminova; Ester Casal; Manuel Hermida; Isaac Blickstein
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Publication Detail:
Type:  Journal Article     Date:  2010-08-13
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  38     ISSN:  1619-3997     ISO Abbreviation:  J Perinat Med     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  671-4     Citation Subset:  IM    
Prenatal Diagnosis Center, Hospital Garcia de Orta, Almada, Portugal.
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