Document Detail

The source of Na+ and Cl- activities on the skin surface. Experiences with electrode measurements in children.
MedLine Citation:
PMID:  1151164     Owner:  NLM     Status:  MEDLINE    
We have used ion-specific electrodes in an attempt to map the sodium and chloride activities on the skin under differing surface conditions. The range of values and the standard deviations are so wide that a baseline for the untreated dry skin is precluded. In patients with cystic fibrosis, a wide range of values is also found. For this group, measurements on dry skin taken immediately after washing were in the same low range as for healthy subjects. The range of measurements on the dry skin of newborn infants was similar for full-term infants with reactive sweat glands and for premature infants who failed to show sweating responsiveness to natural reflex stimulation as well as local glandular stimulation with sudorific drugs. For only two conditions have measurements of sodium and chloride activities on the surface of the skin been of value: (1) on the sweat-covered skin for the detection of the high values encountered in cystic fibrosis, and (2) on the dry skin surface, deprived of autonomic innervation (spinal paraplegia), extremely low sodium and chloride activities reflect absent gland activity.
M Green; A V Mascia; H Behrendt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of laboratory and clinical medicine     Volume:  86     ISSN:  0022-2143     ISO Abbreviation:  J. Lab. Clin. Med.     Publication Date:  1975 Sep 
Date Detail:
Created Date:  1975-11-08     Completed Date:  1975-11-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375375     Medline TA:  J Lab Clin Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  494-8     Citation Subset:  AIM; IM    
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MeSH Terms
Child, Preschool
Chlorides / analysis*
Cystic Fibrosis
Infant, Newborn
Skin / analysis*
Sodium / analysis*
Sweat / analysis*
Reg. No./Substance:
0/Chlorides; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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