Document Detail


The sorption of isosorbide-5-mononitrate to intravenous delivery systems.
MedLine Citation:
PMID:  1979625     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The sorption of isosorbide-5-mononitrate, diluted in 0.9% NaCl or 10% glucose solutions, to intravenous delivery systems was investigated. Infusion bags, burettes, a syringe, infusion tubings and end-line filters were tested in static and in dynamic experiments. No clinically significant sorption was detected during those experiments. The use of PVC tubings of different hardness did not influence the results.
Authors:
C De Muynck; F Colardyn; J P Remon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of pharmacy and pharmacology     Volume:  42     ISSN:  0022-3573     ISO Abbreviation:  J. Pharm. Pharmacol.     Publication Date:  1990 Jun 
Date Detail:
Created Date:  1991-01-25     Completed Date:  1991-01-25     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  0376363     Medline TA:  J Pharm Pharmacol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  433-4     Citation Subset:  IM    
Affiliation:
Laboratory of Pharmaceutical Technology, State University of Gent, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Adsorption
Glucose / chemistry
Hardness
Infusions, Intravenous
Isosorbide Dinitrate / analogs & derivatives*,  chemistry
Plasticizers
Polyvinyl Chloride
Rubber
Sodium Chloride
Solutions
Syringes
Chemical
Reg. No./Substance:
0/Plasticizers; 0/Solutions; 16051-77-7/isosorbide-5-mononitrate; 50-99-7/Glucose; 7647-14-5/Sodium Chloride; 87-33-2/Isosorbide Dinitrate; 9002-86-2/Polyvinyl Chloride; 9006-04-6/Rubber

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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