Document Detail


A soluble-polymer system for the asymmetric transfer hydrogenation of ketones.
MedLine Citation:
PMID:  15287789     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
The appropriate combination of methacrylate polymers permits the synthesis of a soluble polymer for use in ruthenium(II)-catalyzed asymmetric transfer hydrogenation reactions. Using a 7:3 copolymer of a poly(ethylene glycol) ester and a hydroxyethyl ester, a derived ruthenium(II)/norephedrine complex catalyses reduction of acetophenone in up to 95% yield and 81% ee.
Authors:
Stephanie Bastin; Richard J Eaves; Christopher W Edwards; Osamu Ichihara; Mark Whittaker; Martin Wills
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of organic chemistry     Volume:  69     ISSN:  0022-3263     ISO Abbreviation:  J. Org. Chem.     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-08-03     Completed Date:  2004-09-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985193R     Medline TA:  J Org Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5405-12     Citation Subset:  -    
Copyright Information:
Copyright 2004 American Chemical Society
Affiliation:
Department of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.
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