Document Detail

The soft tissue response to contaminated and cleaned titanium surfaces using CO2 laser, citric acid and hydrogen peroxide. An experimental study in the rat abdominal wall.
MedLine Citation:
PMID:  11168199     Owner:  NLM     Status:  MEDLINE    
The soft tissue response to clinically retrieved and decontaminated cover screws was evaluated in a rat model. The cover screws were cleaned by using citric acid, sterile water, hydrogen peroxide and CO2 laser alone or with a combination of these. In addition, decontaminated but not cleaned and unused cover screws were used as negative and positive controls, respectively. After cleaning the cover screws were implanted in the abdominal wall of the rat for 6 weeks. The thickness of the fibrous capsule and the number of macrophages within the capsule were measured by means of light microscopical morphometry. As compared to the negative control, CO2 laser on dry surface, CO2 laser + hydrogen peroxide and the positive control had statistically significant thinner fibrous capsules. As compared to the positive, only laser alone resulted in a similar tissue response. It is concluded that CO2 laser used alone or in combination with hydrogen peroxide may be used clinically for sufficient decontamination of titanium surfaces.
J Mouhyi; L Sennerby; J Van Reck
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical oral implants research     Volume:  11     ISSN:  0905-7161     ISO Abbreviation:  Clin Oral Implants Res     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2001-02-19     Completed Date:  2001-04-19     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  9105713     Medline TA:  Clin Oral Implants Res     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  93-8     Citation Subset:  D    
Department of Oral and Maxillofacial Surgery, St Pierre University Hospital, Brussels, Belgium.
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MeSH Terms
Citric Acid
Decontamination / instrumentation,  methods*
Hydrogen Peroxide
Implants, Experimental*
Macrophage Activation
Rats, Sprague-Dawley
Statistics, Nonparametric
Reg. No./Substance:
7440-32-6/Titanium; 77-92-9/Citric Acid; 7722-84-1/Hydrogen Peroxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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