Document Detail


A snake bite by the Burrowing Asp, Atractaspis engaddensis.
MedLine Citation:
PMID:  9920494     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During routine milking of a group of Burrowing Asps Atractaspis engaddensis, one of the authors was bitten in the index finger by one fang, as is characteristic of bites by snakes of the genus. Local effects, oedema, erythema and numbness appeared within minutes, followed by systemic effects, including general weakness, sweating, pallor, fluctuations in the level of consciousness, vomiting and watery non-bloody diarrhoea. Gross oedema of the hand developed and extended up to the forearm. Two hours after admission to the hospital, blood pressure rose to 180/110, the ECG showed normal sinus rhythm and no signs of atrioventricular conduction block. An ECG obtained 24 h after the bite showed new T-wave inversions in leads V5 + 6, which gradually returned to baseline within several days. The local effects healed during the following weeks, but some discoloration and tenderness remained even 10 months after the bite. A maximal exercise (SPECT) study carried out five months after the bite was normal and a multigated radionuclear ventriculogram (MUGA) showed normal left-ventricular function. It may be assumed that the rise in blood pressure observed in this case reflects a systemic vasoconstrictive effect of the sarafotoxins, while the ST changes may have been caused by the direct effect of the toxins on the heart or indirectly by vasoconstriction of the coronary arteries. However, ischaemia secondary to a rise in blood pressure or to excitement could also explain the observed ECG-changes.
Authors:
D Kurnik; Y Haviv; E Kochva
Related Documents :
3723394 - Effects of kb-944, a novel calcium antagonist, in several models of canine myocardial i...
2952824 - Effects of treadmill and pacing stress testing on peripheral arterial thromboxane, plat...
20516504 - Resting pd/pa measured with intracoronary pressure wire strongly predicts fractional fl...
24574584 - Cricoid pressure: where do we stand?
7572024 - Adenosine for per-operative blood pressure control in an infant with neuroblastoma.
16678424 - Circadian blood pressure variation after acute stroke.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Toxicon : official journal of the International Society on Toxinology     Volume:  37     ISSN:  0041-0101     ISO Abbreviation:  Toxicon     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-04-13     Completed Date:  1999-04-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1307333     Medline TA:  Toxicon     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  223-7     Citation Subset:  IM    
Affiliation:
Department of Medicine A, Sheba Medical Center, Tel Hashomer, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Edema / pathology
Electrocardiography / drug effects
Erythema / pathology
Fingers / pathology
Humans
Male
Snake Bites / pathology*
Tomography, Emission-Computed, Single-Photon
Viperidae*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Sex-linked variation of Loxosceles intermedia spider venoms.
Next Document:  The smooth muscle relaxant effects of venom from the inland taipan (Oxyuranus microlepidotus).