Document Detail


A skincare containing retinol adenosine and hyaluronic acid optimises the benefits from a type A botulinum toxin injection.
MedLine Citation:
PMID:  23016532     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Abstract Introduction: A monocentre double-blind two parallel group clinical study was conducted to assess whether a new skincare regimen containing retinol, adenosine and hyaluronic acid, applied after the injection of botulinum toxin A to the glabellar area, provided a beneficial effect. Material and methods. Standardised photographs acquired using LifeViz cameras and zoomed pictures of the glabella and of the crow's feet areas were analysed with automatic well-defined procedures. Perceived efficacy and tolerance were also analysed by comparison between the two groups. Results: A beneficial effect versus placebo-treated group was proven in the group having topically applied the new skincare regimen for 2 months following botulinum toxin A injection with no touch up after 1 month. 3D image analysis showed more rapid results on D10 and enhanced efficacy on M2. Moreover, a beneficial effect independent of injection was measured in the crow's feet area, and analysis of the self-evaluation questionnaire showed enhanced efficacy perceived by the volunteers. Conclusion: A specially developed skincare regimen applied immediately after botulinum toxin A injection completes the beneficial effect of the injection on the glabellar area and offers clinical benefits in fine lines, wrinkles and smoothness on the whole face.
Authors:
Benjamin Ascher; Chantal Fanchon; Leila Kanoun-Copy; Anne Bouloc; Florence Benech
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology     Volume:  14     ISSN:  1476-4180     ISO Abbreviation:  J Cosmet Laser Ther     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136419     Medline TA:  J Cosmet Laser Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  234-8     Citation Subset:  IM    
Affiliation:
Clinique Iena , Paris , France.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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