Document Detail

The skeletal muscle-metabolism axis in prostate-cancer therapy.
MedLine Citation:
PMID:  23215572     Owner:  NLM     Status:  In-Data-Review    
To the Editor: Basaria and Bhasin (Sept. 6 issue)(1) report that men with prostate cancer who are receiving androgen-deprivation therapy have multiple adverse events. The authors included follistatin and irisin between the main targets of investigation to prevent and treat the metabolic side effects associated with androgen-deprivation therapy. It has been shown that exercise induces a marked increase in plasma and muscle follistatin and irisin.(2)-(4) Follistatin expression changes in both the muscle and fat of diabetic rats and can be modulated by exercise.(5) Concentrations of irisin increase significantly after exercise in both mice and humans, and irisin levels in . . .
Fabian Sanchis-Gomar
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The New England journal of medicine     Volume:  367     ISSN:  1533-4406     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2257-8     Citation Subset:  AIM; IM    
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