Document Detail


A six-year experience with the omnicarbon valve in North American patients.
MedLine Citation:
PMID:  15383055     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: We studied the results of an all-carbon monoleaflet valve prosthesis (the Omnicarbon) in a North American population. METHODS: Patients were recalled to our valve clinic for complete evaluation, including echocardiography, laboratory tests, and physician examination. This experience includes 108 Omnicarbon valve implants. We report the results of single aortic (AVR) or mitral (MVR) valve replacement. RESULTS: Patients' ages ranged from 40 to 83 (mean: 63 +/- 9 years), and most were male (60%, 59/98). Preoperatively, 71% were NYHA Classes III/IV, while most patients are now Classes I/II (86%). AVR predominated (63%, 62/98), and many patients (44%, 43/98) underwent cardiac procedures either previously or concomitant with valve replacement. Hospital mortality was 6.1% (6/98). Predicted hospital mortality using the Parsonnet additive risk model averaged 12.1%. Currently, four patients cannot be located (96% accountability). Overall, hematology indicated low hemolysis-lactate dehydrogenase: 691 +/- 184 IU/L (112%+/- 30% upper normal), reticulocytes: 1.8%+/- 0.7%, and red blood cells (10(6)/mm(3)): 4.41 +/- 0.50 (males)/4.16 +/- 0.50 (females). International normalized ratio averaged 2.67 +/- 0.72. Doppler echocardiography values were acceptable and comparable to other mechanical valves. Five-year survival (hospital death included) is 86%+/- 4%. At 5 years, freedom from any thromboembolic event is 99%+/- 1%, and freedom from bleeding is 97%+/- 2%. Endocarditis and nonstructural dysfuction also occurred at low rates (99%+/- 1% freedom at five years), and no structural failure or hemolytic anemia was observed during the 343 patient-years (mean: 3.7 +/- 1.6 years). CONCLUSIONS: Good hematology and hemodynamics, along with remarkably low complication rates, demonstrate that the Omnicarbon valve meets contemporary performance expectations.
Authors:
Julie Carrier; Javier Teijeira; David Greentree; Sylvie Gagnon; Marie-Claude Brochu; Chantal Paulin; Serge Lepage; Michel Côté
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of cardiac surgery     Volume:  19     ISSN:  0886-0440     ISO Abbreviation:  J Card Surg     Publication Date:    2004 Sep-Oct
Date Detail:
Created Date:  2004-09-22     Completed Date:  2005-02-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8908809     Medline TA:  J Card Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  432-7     Citation Subset:  IM    
Affiliation:
Division of Cardiovascular and Thoracic Surgery, Faculty of Medicine and CHUS, Sherbrooke University, Sherbrooke, Quebec, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Aortic Valve*
Female
Heart Valve Diseases / surgery
Heart Valve Prosthesis*
Heart Valve Prosthesis Implantation / instrumentation*
Hemodynamics
Humans
Male
Middle Aged
Mitral Valve*
North America

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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