Document Detail

A single session of resistance exercise enhances insulin sensitivity for at least 24 h in healthy men.
MedLine Citation:
PMID:  15761746     Owner:  NLM     Status:  MEDLINE    
The aim of the present study was to determine whether a single session of resistance exercise improves whole-body insulin sensitivity in healthy men for up to 24 h. Twelve male subjects (23 +/- 1 years) were studied over a period of 4 days during which they consumed a standardized diet, providing 0.16 +/- 0.01 containing 15 +/- 0.1 energy% (En%) protein, 29 +/ -0.1 En% fat and 55 +/- 0.3 En% carbohydrate. Insulin sensitivity was determined 24 h before and 24 h after a single resistance exercise session (8 sets of 10 repetitions at 75% of 1 repetition maximum for two leg exercise tasks) using an intravenous insulin tolerance test. Insulin sensitivity index was calculated by the decline in arterial blood glucose concentration following intravenous administration of a single bolus of human insulin (0.075 fat free mass). Basal glucose and insulin concentrations were not changed up to 24 h after the resistance exercise. However, a substantial 13+/-5% improvement in whole-body insulin sensitivity was observed, 24 h after the resistance exercise (P < 0.05). This study shows that even a single session of resistance exercise improves whole-body insulin sensitivity for up to 24 h in healthy men, which is consistent with earlier observations following endurance exercise tasks.
René Koopman; Ralph J F Manders; Antoine H G Zorenc; Gabby B J Hul; Harm Kuipers; Hans A Keizer; Luc J C van Loon
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2005-03-11
Journal Detail:
Title:  European journal of applied physiology     Volume:  94     ISSN:  1439-6319     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-04-27     Completed Date:  2005-08-11     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  180-7     Citation Subset:  IM    
Department of Human Biology, Maastricht University, The Netherlands.
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MeSH Terms
Adaptation, Physiological / physiology
Blood Glucose / analysis*
Exercise / physiology*
Glucose Clamp Technique*
Injections, Intravenous
Insulin / administration & dosage*
Insulin Resistance / physiology*
Muscle, Skeletal / drug effects,  physiology*
Physical Endurance / physiology*
Physical Exertion / physiology*
Reg. No./Substance:
0/Blood Glucose; 11061-68-0/Insulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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