Document Detail

A single-blinded comparative study between the use of glycolic acid 70% peel and the use of topical nanosome vitamin C iontophoresis in the treatment of melasma.
MedLine Citation:
PMID:  22360337     Owner:  NLM     Status:  In-Data-Review    
Background  Melasma is a common pigmentary disorder. Despite the availability of a wide range of skin-lightening treatments, melasma of skin remains a therapeutic challenge. Objective  The aim of this study was to evaluate the efficacy and safety of nanosome vitamin C iontophoresis and to compare the therapeutic effects of nanosome vitamin C iontophoresis vs. glycolic acid peel 70% in the treatment of melasma in Egyptian women. Methods  This study included 14 patients of melasma with skin type IV-V taken for a right-left comparison study of six sessions. Glycolic acid 70% peel was applied on the right side, whereas nanosome vitamin C was applied by iontophoresis on the other side. The results are evaluated using the melasma area and severity index score and with photographs at baseline and after six sessions. Also the photographs were evaluated by two single-blinded physicians before and after sessions. Results  Both sides were improved, but the side treated with nanosome vitamin C showed better results. Side effects were few and transient. Conclusion  We concluded that nanosome vitamin C is a new, safe and effective, easy and painless method in the treatment of melasma.
Rehab Mohamed Sobhi; Ahmed Mohamed Sobhi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cosmetic dermatology     Volume:  11     ISSN:  1473-2165     ISO Abbreviation:  J Cosmet Dermatol     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-02-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101130964     Medline TA:  J Cosmet Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  65-71     Citation Subset:  IM    
Copyright Information:
© 2012 Wiley Periodicals, Inc.
Department of Dermatology, Faculty of Medicine, Cairo University, Cairo, Egypt Department of Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt.
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