Document Detail


The simultaneous electrochemical detection of ascorbic acid, dopamine, and uric acid using graphene/size-selected Pt nanocomposites.
MedLine Citation:
PMID:  21324669     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In this study, a graphene/Pt-modified glassy carbon (GC) electrode was created to simultaneously characterize ascorbic acid (AA), dopamine (DA), and uric acid (UA) levels via cyclic voltammetry (CV) and differential pulse voltammetry (DPV). During the preparation of the nanocomposite, size-selected Pt nanoparticles with a mean diameter of 1.7nm were self-assembled onto the graphene surface. In the simultaneous detection of the three aforementioned analytes using CV, the electrochemical potential differences among the three detected peaks were 185mV (AA to DA), 144mV (DA to UA), and 329mV (AA and UA), respectively. In comparison to the CV results of bare GC and graphene-modified GC electrodes, the large electrochemical potential difference that is achieved via the use of the graphene/Pt nanocomposites is essential to the distinguishing of these three analytes. An optimized adsorption of size-selected Pt colloidal nanoparticles onto the graphene surface results in a graphene/Pt nanocomposite that can provide a good platform for the routine analysis of AA, DA, and UA.
Authors:
Chia-Liang Sun; Hsin-Hsien Lee; Jen-Ming Yang; Ching-Chou Wu
Related Documents :
20399499 - Effects of exogenous salicylic acid pre-treatment on cadmium toxicity and leaf lipid co...
8981059 - Hypochlorous acid and its pharmacological antagonism: an update picture.
12531249 - Melatonin preserves arachidonic and docosapentaenoic acids during ascorbate-fe2+ peroxi...
1872469 - Iodometric measurement of lipid hydroperoxides in human plasma.
21383659 - Microwave-assisted extraction of phenolic antioxidants from potato peels.
21557719 - Tolfenamic acid interrupts the de novo synthesis of the β-amyloid precursor protein an...
15612259 - Isolation and characterization of the immunoglobin of pike (esox lucius l.).
16720369 - A novel electrochemical biosensor for the detection of uric acid and adenine.
12907129 - Effects of fatty acids on the growth of caco-2 cells.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-25
Journal Detail:
Title:  Biosensors & bioelectronics     Volume:  -     ISSN:  1873-4235     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-2-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001289     Medline TA:  Biosens Bioelectron     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier B.V. All rights reserved.
Affiliation:
Department of Chemical and Materials Engineering, Chang Gung University, Kwei-Shan, Tao-Yuan 333, Taiwan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Palladium nanoparticle/chitosan-grafted graphene nanocomposites for construction of a glucose biosen...
Next Document:  Promoter proximal pausing and the control of gene expression.