Document Detail


A simple and reliable method for delivering small fluid volumes to the brain of a freely moving rat.
MedLine Citation:
PMID:  9128165     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A stepper motor-powered micropump for making intracerebral microinjections in freely moving animals is described. The micropump is capable of delivering fluid volumes of up to 20 microl in steps of 17 nl The system does not require a fluid swivel, delivers injections rapidly, maintains long-term calibration accuracy and is not susceptible to blockage of the cannula.
Authors:
G W Hesse; J R Stellar; J Chevrette
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neuroscience methods     Volume:  72     ISSN:  0165-0270     ISO Abbreviation:  J. Neurosci. Methods     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-06-30     Completed Date:  1997-06-30     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7905558     Medline TA:  J Neurosci Methods     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  35-8     Citation Subset:  IM    
Affiliation:
Northeastern University, Boston, MA 02115, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain / physiology*
Infusion Pumps
Locomotion / physiology
Microinjections / instrumentation*,  methods*
Rats

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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