| A simple and rapid approach to hypokalemic paralysis. | |
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MedLine Citation:
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PMID: 14574658 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hypokalemia with paralysis (HP) is a potentially reversible medical emergency. It is primarily the result of either hypokalemic periodic paralysis (HPP) caused by an enhanced shift of potassium (K(+)) into cells or non-HPP resulting from excessive K(+) loss. Failure to make a distinction between HPP and non-HPP could lead to improper management. The use of spot urine for K(+) excretion rate and evaluation of blood acid-base status could be clinically beneficial in the diagnosis and management. A very low rate of K(+) excretion coupled with the absence of a metabolic acid-base disorder suggests HPP, whereas a high rate of K(+) excretion accompanied by either metabolic alkalosis or metabolic acidosis favors non-HPP. The therapy of HPP requires only small doses of potassium chloride (KCl) to avoid rebound hyperkalemia. In contrast, higher doses of KCl should be administered to replete the large K(+) deficiency in non-HPP. |
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Authors:
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Shih-Hua Lin; Jainn-Shiun Chiu; Chin-Wang Hsu; Tom Chau |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The American journal of emergency medicine Volume: 21 ISSN: 0735-6757 ISO Abbreviation: Am J Emerg Med Publication Date: 2003 Oct |
Date Detail:
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Created Date: 2003-10-23 Completed Date: 2003-12-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8309942 Medline TA: Am J Emerg Med Country: United States |
Other Details:
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Languages: eng Pagination: 487-91 Citation Subset: IM |
Affiliation:
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Division of Nephrology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, R.O.C. L521116@ndmctsgh.edu.tw |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acid-Base Equilibrium Adult Bartter Syndrome / complications, diagnosis, therapy Diagnosis, Differential Emergency Medical Services / methods Female Humans Hyperthyroidism / complications, diagnosis, therapy Hypokalemic Periodic Paralysis / blood, complications, diagnosis*, therapy*, urine Infusions, Intravenous Male Potassium / urine Potassium Chloride / administration & dosage Sjogren's Syndrome / diagnosis, therapy Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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7440-09-7/Potassium; 7447-40-7/Potassium Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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