| A simple quantitative assay of vascular plasminogen activator--not only stimulated fibrinolytic activity but also basal fibrinolytic activity are correlated with venous fibrinolytic activity. | |
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MedLine Citation:
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PMID: 2098097 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A simple method for the quantitative assay of vascular plasminogen activator is described. From 24 chronic renal failure patients who were undergoing surgery for A/V fistular or shunt construction, small pieces of artery (mean 7.8 mg, range 3.0-18.5 mg) and vein (mean 4.5 mg, range 3.0-8.8 mg) were used. The fibrinolytic activity was assayed on a well-controlled fibrin plate by only distilled water immersion and incubation at 37 degrees C. Basal fibrinolytic activity was correlated with venous fibrinolytic activity (r = 0.773, p less than 0.0001) and with arterial fibrinolytic activity (r = 0.55, 0.005 less than p less than 0.01). The increment of fibrinolytic activity by venous occlusion was correlated to venous fibrinolytic activity (r = 0.849, p less than 0.0001) but not to arterial fibrinolytic activity (r = 0.34, 0.1 less than p less than 0.25). |
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Authors:
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S Y Hong; C S Lee |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Korean journal of internal medicine Volume: 5 ISSN: 1226-3303 ISO Abbreviation: Korean J. Intern. Med. Publication Date: 1990 Jul |
Date Detail:
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Created Date: 1991-07-30 Completed Date: 1991-07-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8712418 Medline TA: Korean J Intern Med Country: KOREA |
Other Details:
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Languages: eng Pagination: 87-92 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Soonchunhyang University Chunan Hospital, Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Vessels
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enzymology* Fibrinolysis Humans Plasminogen Activators / analysis* |
| Chemical | |
Reg. No./Substance:
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EC 3.4.21.-/Plasminogen Activators |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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