Document Detail


A simple photokinetic method for the determination of nitroprusside in biological and pharmaceutical samples.
MedLine Citation:
PMID:  1908317     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A simple method has been developed for the determination of nitroprusside in human serum and pharmaceutical preparations. The new method is based on the strong inhibitory effect of nitroprusside on the photochemical reduction of phloxin by ethylenediaminetetra-acetic acid. The rate measurements are accomplished very simply by measuring the time needed for the absorbance to be reduced to 1/10th of its initial value. Optimal conditions for the determination of nitroprusside at concentrations of 15-200 ng ml-1 are described.
Authors:
T Pérez-Ruiz; M C Martínez-Lozano; V Tomás; C López-Balsera
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pharmaceutical and biomedical analysis     Volume:  9     ISSN:  0731-7085     ISO Abbreviation:  J Pharm Biomed Anal     Publication Date:  1991  
Date Detail:
Created Date:  1991-09-26     Completed Date:  1991-09-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8309336     Medline TA:  J Pharm Biomed Anal     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  123-8     Citation Subset:  IM    
Affiliation:
Department of Analytical Chemistry, Faculty of Sciences, University of Murcia, Spain.
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MeSH Terms
Descriptor/Qualifier:
Edetic Acid
Humans
Hydrogen-Ion Concentration
Indicators and Reagents
Nitroprusside / analysis*
Oxidation-Reduction
Photochemistry
Tablets
Temperature
Chemical
Reg. No./Substance:
0/Indicators and Reagents; 0/Tablets; 15078-28-1/Nitroprusside; 60-00-4/Edetic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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