Document Detail


A simple greedy algorithm for reconstructing pedigrees.
MedLine Citation:
PMID:  23164633     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
This paper introduces a simple greedy algorithm for searching for high likelihood pedigrees using micro-satellite (STR) genotype information on a complete sample of related individuals. The core idea behind the algorithm is not new, but it is believed that putting it into a greedy search setting, and specifically the application to pedigree learning, is novel. The algorithm does not require age or sex information, but this information can be incorporated if desired. The algorithm is applied to human and non-human genetic data and in a simulation study.
Authors:
Robert G Cowell
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-16
Journal Detail:
Title:  Theoretical population biology     Volume:  -     ISSN:  1096-0325     ISO Abbreviation:  Theor Popul Biol     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0256422     Medline TA:  Theor Popul Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Inc.
Affiliation:
Faculty of Actuarial Science and Insurance, Cass Business School, 106 Bunhill Row, London EC1Y 8TZ, UK. Electronic address: rgc@city.ac.uk.
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