| A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of β-ketoesters as cleavable probes. | |
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MedLine Citation:
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PMID: 22430672 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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β-ketoesters are robust probes for labeling sulfenic acid (-SOH) proteins allowing quantitative cleavage of the tag for improved analysis of the labeled peptides by MS. |
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Authors:
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Jiang Qian; Revati Wani; Chananat Klomsiri; Leslie B Poole; Allen W Tsang; Cristina M Furdui |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2012-03-20 |
Journal Detail:
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Title: Chemical communications (Cambridge, England) Volume: 48 ISSN: 1364-548X ISO Abbreviation: Chem. Commun. (Camb.) Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-03-29 Completed Date: 2012-07-23 Revised Date: 2013-04-30 |
Medline Journal Info:
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Nlm Unique ID: 9610838 Medline TA: Chem Commun (Camb) Country: England |
Other Details:
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Languages: eng Pagination: 4091-3 Citation Subset: IM |
Copyright Information:
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This journal is © The Royal Society of Chemistry 2012 |
Affiliation:
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Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Survival Cysteine / analogs & derivatives*, analysis Esters / chemistry Ketones / chemistry Mice Models, Molecular NIH 3T3 Cells Proteins / chemistry* Spectrometry, Mass, Electrospray Ionization* Staining and Labeling Sulfenic Acids / analysis* |
| Grant Support | |
ID/Acronym/Agency:
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R01 CA136810/CA/NCI NIH HHS; R01 CA136810/CA/NCI NIH HHS; R33 CA126659/CA/NCI NIH HHS; R33 CA126659/CA/NCI NIH HHS; R33 CA126659Z/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Esters; 0/Ketones; 0/Proteins; 0/Sulfenic Acids; 52-90-4/Cysteine; FB8KIA847T/cysteinesulfenic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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