Document Detail

The significance of right-sided chest leads in exercise testing for the detection of right ventricular dysfunction post myocardial infarction of the inferior wall.
MedLine Citation:
PMID:  19651448     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: The incorporation of right-sided chest leads (V(3)R-V(5)R) into the standard exercise testing has been reported to improve its diagnostic accuracy. The purpose of this study was to evaluate the ability of exercise testing in detecting right ventricular (RV) dysfunction post myocardial infarction (MI) of the inferior wall, using additional V(3)R-V(5)R leads.
METHODS: We studied 133 patients (59±5 years, 81 males) with a history of inferior MI due to right coronary artery obstruction (affirmed with coronary angiography). All patients underwent an echocardiographic assessment of RV function 4 weeks after discharge and an exercise treadmill test in order to detect possible RV dysfunction. Recordings during exercise were obtained with the standard 12 leads plus V(3)R-V(5)R.
RESULTS: From 133 patients, 97 (group A) presented with normal right ventricle according to the echocardiographic study while the rest 36 patients (group B) presented with RV dysfunction. Maximal exercise-induced ST-segment deviation (in mm) was similar in the standard 12 leads for the 2 groups (2.1±0.4 vs 1.8±0.3, p=NS) while in V(3)R-V(5)R it was greater in group B (0.7±0.3 vs 1.4±0.4, p<0.05). Sensitivity, positive prognostic value, negative prognostic value and accuracy of exercise testing in detecting RV dysfunction were all improved using V(3)R-V(5)R (78 vs 47%, 39 vs 29%, 87 vs 75%, 62 vs 55% respectively, p<0.05 for all) while specificity was not deteriorated (56 vs 58%, p=NS).
CONCLUSIONS: The addition of right-sided chest leads (V(3)R-V(5)R) improves the diagnostic ability of standard exercise testing in detecting and especially in excluding RV dysfunction post inferior MI.
Andreas Michaelides; Dimitris Tousoulis; Charalampos Liakos; Konstantina Aggeli; Charalambos Antoniades; Gregory Vyssoulis; Leonidas Raftopoulos; Dimitrios Soulis; Konstantinos Toutouzas; Christodoulos Stefanadis
Related Documents :
21615668 - Exercise training increases adipose tissue glut4 expression in patients with type 2 dia...
6488228 - Incidence and prognostic significance of symptomatic and asymptomatic exercise-induced ...
7838678 - Effects of the reactive oxygen species hypochlorous acid and hydrogen peroxide on force...
354368 - Submaximal exercise testing after acute myocardial infarction: myocardial scintigraphic...
23830128 - Refractoriness to exercise challenge: a review of the mechanisms old and new.
19498098 - Subcellular movement and expression of hsp27, alphab-crystallin, and hsp70 after two bo...
Publication Detail:
Type:  Journal Article     Date:  2009-08-03
Journal Detail:
Title:  International journal of cardiology     Volume:  146     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  330-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.
Exercise Laboratory, 1st University Department of Cardiology, Athens Medical School, Hippokration Hospital, Athens, Greece.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  In vitro effects of metal pollution on Mediterranean sponges: species-specific inhibition of 2',5'-o...
Next Document:  Additive beneficial effects of atorvastatin combined with amlodipine in patients with mild-to-modera...