Document Detail


The significance of mean platelet volume on diagnosis and management of adenomyosis.
MedLine Citation:
PMID:  23348163     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Aim The present study was designed to assess the signiicance of mean platelet volume on the pathogenesis and management of adenomyosis. Methods A total of 26 patients out of 123 with pathologically conirmed adenomyosis in hysterectomy specimens without concomitant gynecological pathology were selected for the study. Control group was consisted of 24 symptom-free subjects out of 35, with normal smear test and without infection. Groups were compared in terms of mean platelet volumes and platelet counts. Results The mean platelet volume values of patients with pathologically conirmed adenomyosis were found to be signiicantly higher than the values in the control group (9.3±0.8 fL versus 7.3±0.8 fL; p less 0.05). Platelet count comparison between the two groups showed no statistical signiicance (p>0.05). Conclusion This study conirms the previous studies indicating endometriosis and adenomyosis as inlammatory processes. As a result, mean platelet volume has shown to be a signiicant clinical marker for chronic inlammatory process of adenomyosis and endometriosis. This basic inding should be supported by new studies concerning the correlation of mean platelet volume levels with severity and duration of the disease, as well as response of mean platelet volume levels to therapies targeting chronic inlammatory process in adenomyosis and endometriosis pathogenesis.
Authors:
Serkan Bodur; Ismet Gün; Mustafa Alpaslan Babayigit
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina     Volume:  10     ISSN:  1840-0132     ISO Abbreviation:  Med Glas Ljek komore Zenicko-doboj kantona     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101250177     Medline TA:  Med Glas Ljek komore Zenicko-doboj kantona     Country:  Bosnia and Hercegovina    
Other Details:
Languages:  eng     Pagination:  59-62     Citation Subset:  IM    
Affiliation:
1Department of Obstetrics and Gynecology, Maresal Cakmak Millitary Hospital, Erzurum, 2Department of Obstetrics and Gynecology, GATA Haydarpasa Training Hospital, İstanbul, 3Turkish Military Health Command, Ankara; Turkey.
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