| The significance of immunoglobulins in the treatment of patients with sepsis and septic shock. | |
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MedLine Citation:
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PMID: 9623363 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Inappropriate body response is, besides the infectious agent, responsible for the genesis of sepsis and septic shock. It is non-specific and in cascade of events it can hardly be controlled. The results of immunoglobulins administration compared to the disease course and outcome have been compared and analyzed in 135 patients with sepsis and septic shock. A hundred and four patients were treated for sepsis. Immunoglobulins were administered to 18, of whom 17 patients (94.55%) were cured, while one (5.55%) developed septic shock with lethal outcome. Out of the other 86 patients who did not receive immunoglobulins, 82 (95.35%) were cured, while in 4 (4.65%) patients the outcome was lethal. No difference was observed between studied groups. Among 31 patients with septic shock, 13 received immunoglobulins. Seven (53.85%) patients were cured, and 6 (46.15%) died. In relation to the favorable disease outcome the difference was observed (statistically non-significant) in the group that received immunoglobulins, compared to the group that did not (53.85% vs. 44.45%). The importance of immunoglobulins administration, in sepsis and septic shock should be emphasized. |
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Authors:
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I Bojić; V Begović; Z Trnjak; M Dokić |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Vojnosanitetski pregled. Military-medical and pharmaceutical review Volume: 55 ISSN: 0042-8450 ISO Abbreviation: Vojnosanit Pregl Publication Date: 1998 Mar-Apr |
Date Detail:
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Created Date: 1998-08-24 Completed Date: 1998-08-24 Revised Date: 2008-01-09 |
Medline Journal Info:
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Nlm Unique ID: 21530700R Medline TA: Vojnosanit Pregl Country: YUGOSLAVIA |
Other Details:
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Languages: eng Pagination: 75-8 Citation Subset: IM |
Affiliation:
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Military Medical Academy, Clinic for Infectious and Tropical Diseases, Belgrade. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Female Humans Immunoglobulins, Intravenous / therapeutic use* Male Middle Aged Sepsis / mortality, therapy* Shock, Septic / mortality, therapy* Survival Rate |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulins, Intravenous |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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