Document Detail

The significance of frontal system disorders for medical practice and health policy.
MedLine Citation:
PMID:  7841805     Owner:  NLM     Status:  MEDLINE    
In major chronic diseases, apathy or impaired executive cognitive function (ECF) can reduce the patient's ability to cope with the disease and its treatment and to maintain personal safety, dignity, and goal-directed activity. Psychometric and imaging studies support a causal role for frontal system dysfunction. The view that frontal system dysfunction mediates or aggravates disability in a wide range of psychiatric and nonpsychiatric disorders 1) motivates further research on how ECF deficits interact with specific physical impairments to produce disability; 2) supports policies that base entitlements to care on ECF impairments; and 3) suggests the need for a vigorous search for drugs that prevent or palliate prefrontal dysfunction, especially the syndromes of apathy and impaired ECF.
B S Fogel
Related Documents :
25398915 - Disseminated cladophialophora bantiana disease in a patient with prediabetes.
23318145 - Alglucosidase alfa enzyme replacement therapy as a therapeutic approach for glycogen st...
8531175 - Diagnosis of inflammatory and infectious diseases of the central nervous system in dogs...
7988965 - Systemic and ocular findings in 169 prospectively studied child deaths: retinal hemorrh...
20075495 - Neural stem cell niches and homing: recruitment and integration into functional tissues.
22925465 - Induced pluripotent stem cell technology for disease modeling and drug screening with e...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of neuropsychiatry and clinical neurosciences     Volume:  6     ISSN:  0895-0172     ISO Abbreviation:  J Neuropsychiatry Clin Neurosci     Publication Date:  1994  
Date Detail:
Created Date:  1995-03-09     Completed Date:  1995-03-09     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8911344     Medline TA:  J Neuropsychiatry Clin Neurosci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  343-7     Citation Subset:  IM    
Department of Psychiatry and Human Behavior, Brown University School of Medicine, Providence, Rhode Island 02912.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Activities of Daily Living / psychology
Brain Damage, Chronic / physiopathology,  psychology,  rehabilitation
Delirium, Dementia, Amnestic, Cognitive Disorders / physiopathology*,  psychology,  rehabilitation
Disability Evaluation*
Eligibility Determination
Frontal Lobe / physiopathology*
Health Policy*
Managed Care Programs

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Characterization of porcine kidney neutral glycosphingolipids: identification of a carbohydrate anti...
Next Document:  Working memory dysfunction in schizophrenia.