Document Detail

The significance of anti-C sensitization in pregnancy.
MedLine Citation:
PMID:  3141104     Owner:  NLM     Status:  MEDLINE    
A study of maternal blood samples from 280,000 pregnancies in an 8-year period has shown 38 examples of anti-C (without anti-D) sensitization. This frequency (0.14/1000 pregnancies) was lower than that previously found for anti-c (0.63/1000 pregnancies) and for anti-D (2.55/1000 pregnancies). Although most of the 38 babies born to mothers with anti-C were unaffected by haemolytic disease of the newborn and none was anaemic at birth, two required exchange transfusion for hyperbilirubinaemia and one a top-up transfusion. Five cord blood samples had a positive direct antiglobulin test.
P J Bowell; M J Inskip; M N Jones
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and laboratory haematology     Volume:  10     ISSN:  0141-9854     ISO Abbreviation:  Clin Lab Haematol     Publication Date:  1988  
Date Detail:
Created Date:  1988-12-01     Completed Date:  1988-12-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7907061     Medline TA:  Clin Lab Haematol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  251-5     Citation Subset:  IM    
Oxford Regional Transfusion Centre, John Radcliffe Hospital.
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MeSH Terms
Erythroblastosis, Fetal / epidemiology*
Infant, Newborn
Middle Aged
Retrospective Studies
Rh-Hr Blood-Group System / immunology*
Reg. No./Substance:
0/Rh-Hr Blood-Group System

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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