| The significance of an across-shift decrease in vital capacity--a re-analysis of a study on subjects exposed to diesel exhaust. | |
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MedLine Citation:
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PMID: 7571167 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Occupational exposure to diesel exhaust may develop acute as well as chronic lung function impairment. In this study, data from an earlier study on a group of subjects working at tunnel construction site were analyzed. The aim of the analysis was to examine the significance of an across-shift decrease in vital capacity with concern to other lung physiological measurements. There were no statistically significant differences, either in the average age, time of employment, vital capacity before a working shift after two days of no exposure, or the distributions of smoking habits and respiratory symptoms, between the eight workers who had an across-shift decrease in vital capacity and the five workers who had not. Subjects with an across-shift decrease in vital capacity had a significantly greater across-shift decrease in residual volume and total lung capacity than subjects without an across-shift decrease in vital capacity. The pathophysiological mechanisms for this across-shift decrease in residual volume is not fully understood. However, an altered defence mechanism in the lung may play a role for a prolonged retention time for the particles in the inhaled diesel exhaust, resulting in the across-shift decrease in residual volume. The results thus suggest that measurements of across-shift vital capacity is of importance in identifying susceptible subjects with occupational exposure to diesel exhaust. |
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Authors:
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M Dahlqvist |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Upsala journal of medical sciences Volume: 100 ISSN: 0300-9734 ISO Abbreviation: Ups. J. Med. Sci. Publication Date: 1995 |
Date Detail:
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Created Date: 1995-11-14 Completed Date: 1995-11-14 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0332203 Medline TA: Ups J Med Sci Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 137-41 Citation Subset: IM |
Affiliation:
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Department of Environmental Technology and Work Science, Royal Institute of Technology, Stockholm, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Humans Male Middle Aged Occupational Exposure* Vehicle Emissions* Vital Capacity* |
| Chemical | |
Reg. No./Substance:
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0/Vehicle Emissions |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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