Document Detail

The significance of Doppler flow in early detection of uterine sarcoma in older primigravida pregnancies.
MedLine Citation:
PMID:  15991529     Owner:  NLM     Status:  MEDLINE    
During a four-year period we analyzed the significance, sensitivity and sensibility of myoma Doppler flow during pregnancy in relation to the course and outcome of the pregnancy and to later histopathological findings. By following 36 older primigravidas with determined myomas, we observed the course of the pregnancies in all trimesters and analyzed myoma Doppler flow. In conditions where the resistance index showed the possibility of uterine sarcoma, the pregnancy was ended by surgery; not only was myomectomy performed but also complete uterine hysterectomy with the previous consent of the patient. Doppler flow was accepted as the authoritative parameter for non-invasive detection of a malignant process. Considering the obstetrical findings, other patients were delivered vaginally or operatively, but after puerperium they were subjected to control examinations and myomectomy because Doppler flow findings did not show any indications of sarcoma. By histopathological analysis, we received benign results in 31 cases, while in four cases where we decided on hysterectomy and surgical delivery, we received malignant results, i.e. leiomyosarcoma. In four cases of performed hysterectomy immediately after cesarean section, the resistance index (RI) of revascularization within the myoma was in the range between RI 0.30 +/- 0.02. Flows within the uterine artery were 0.54 +/- 0.03.
M Gojnic; I Likic; M Pervulov; S Petkovic; A Fazlagic; B Vasiljevic
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of gynaecological oncology     Volume:  26     ISSN:  0392-2936     ISO Abbreviation:  Eur. J. Gynaecol. Oncol.     Publication Date:  2005  
Date Detail:
Created Date:  2005-07-04     Completed Date:  2005-10-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8100357     Medline TA:  Eur J Gynaecol Oncol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  291-3     Citation Subset:  IM    
Medical Faculty of Belgrade, Institute of Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade, Serbia and Montenegro.
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MeSH Terms
Age Factors
Gynecologic Surgical Procedures
Leiomyoma / surgery,  ultrasonography*
Leiomyosarcoma / surgery,  ultrasonography*
Pregnancy Complications, Neoplastic / surgery,  ultrasonography*
Uterine Neoplasms / surgery,  ultrasonography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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