Document Detail

A shortened course of parenteral antibiotic therapy in the management of acute septic arthritis of the hip.
MedLine Citation:
PMID:  10641687     Owner:  NLM     Status:  MEDLINE    
We reviewed 20 consecutive patients with a culture-proven acute septic arthritis of the hip who were treated with a shortened course of parenteral antibiotic therapy after a surgical drainage. Patients were switched over to an oral antibiotic when they showed clinical improvement. Sixteen of the 20 patients had parenteral antibiotic therapy of <10 days, whereas nine of these patients received <7 days of parenteral therapy (mean, 8.2 days). No recurrence of infection, readmission, or osteomyelitis was observed after the discharge. At the follow-up interview (mean, 32 months), 18 patients were completely asymptomatic, and two patients had occasional hip pain with activity but no physical limitations. All 20 patients had normal hip range of motion and gait. Their latest radiographs (mean, 26 months) revealed 11 patients with normal findings, six patients with mild coxa magna, and three patients with a smaller ossific nucleus compared with the unaffected side. We conclude that a community-acquired, acute gram-positive septic arthritis of the hip can be managed safely with a surgical drainage and a shortened course of parenteral antibiotic therapy, which can be switched over to an oral therapy based on the patient's response to the therapy.
H K Kim; B Alman; W G Cole
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric orthopedics     Volume:  20     ISSN:  0271-6798     ISO Abbreviation:  J Pediatr Orthop     Publication Date:    2000 Jan-Feb
Date Detail:
Created Date:  2000-02-03     Completed Date:  2000-02-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8109053     Medline TA:  J Pediatr Orthop     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  44-7     Citation Subset:  IM    
The Hospital for Sick Children, Toronto, Ontario, Canada.
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MeSH Terms
Acute Disease
Anti-Bacterial Agents / administration & dosage*
Arthritis, Infectious / drug therapy*
Child, Preschool
Hip Joint*
Infant, Newborn
Injections, Intravenous
Retrospective Studies
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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