Document Detail


A shape memory polymer dialysis needle adapter for the reduction of hemodynamic stress within arteriovenous grafts.
MedLine Citation:
PMID:  17867367     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A deployable, shape memory polymer adapter is investigated for reducing the hemodynamic stress caused by dialysis needle flow impingement within an arteriovenous graft. Computational fluid dynamics simulations of dialysis sessions with and without the adapter demonstrate that the adapter provides a significant decrease in the wall shear stress. Preliminary in vitro flow visualization measurements are made within a graft model following delivery and actuation of a prototype shape memory polymer adapter. Both the simulations and the qualitative flow visualization measurements demonstrate that the adapter reduces the severity of the dialysis needle flow impingement on the vascular access graft.
Authors:
Jason M Ortega; Ward Small; Thomas S Wilson; William J Benett; Jeffrey M Loge; Duncan J Maitland
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  IEEE transactions on bio-medical engineering     Volume:  54     ISSN:  0018-9294     ISO Abbreviation:  IEEE Trans Biomed Eng     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-09-17     Completed Date:  2007-10-19     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0012737     Medline TA:  IEEE Trans Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1722-4     Citation Subset:  IM    
Affiliation:
Lawrence Livermore National Laboratory, Livermore, CA 94551, USA. ortega17@llnl.gov
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MeSH Terms
Descriptor/Qualifier:
Anastomosis, Surgical / instrumentation*
Biocompatible Materials / chemistry
Blood Pressure
Blood Vessel Prosthesis*
Dialysis / instrumentation*,  methods
Elasticity
Equipment Design
Equipment Failure Analysis
Needles*
Polymers / chemistry*
Stress, Mechanical
Grant Support
ID/Acronym/Agency:
R01EB000462/EB/NIBIB NIH HHS
Chemical
Reg. No./Substance:
0/Biocompatible Materials; 0/Polymers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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