Document Detail

The sex differences in cord-blood cholesterol and fatty-acid levels among Japanese fetuses.
MedLine Citation:
PMID:  9465548     Owner:  NLM     Status:  MEDLINE    
We examined serum cholesterol and fatty-acid levels of cord blood and maternal blood samples collected from 193 Japanese fetuses and their mothers. Our study, which is the largest study of this kind ever conducted in Japan, is the first Japanese study reporting that total, high density lipoprotein (HDL) and non-HDL cholesterol levels in females were statistically significantly higher than those in males; the sex differences of total, HDL and non-HDL cholesterol levels were 8.5 mg/dl (P = 0.002), 4.5 mg/dl (P = 0.004) and 4.1 mg/dl (P = 0.045), respectively. The sex difference of total cholesterol was attributable to both HDL and non-HDL cholesterol. The sex of fetuses didn't show evident differences in cholesterol levels in maternal sera. Fatty-acid levels in cord blood were also higher in female fetuses than in male fetuses. However, none of the differences except for monoene fatty acids were statistically significant. Further investigations seem warranted to elucidate the mechanisms involved in our results.
T Andoh; H Uda; N Yoshimitsu; H Hatano; T Ueda; Y Iwamatsu; S Akiba
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of epidemiology / Japan Epidemiological Association     Volume:  7     ISSN:  0917-5040     ISO Abbreviation:  J Epidemiol     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1998-03-03     Completed Date:  1998-03-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9607688     Medline TA:  J Epidemiol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  226-31     Citation Subset:  IM    
Department of Public Health, Faculty of Medicine, Kagoshima University, Japan.
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MeSH Terms
Cholesterol / blood*
Cholesterol, HDL / blood
Fatty Acids / blood*
Fetal Blood / chemistry*
Infant, Newborn / blood*
Sex Characteristics
Reg. No./Substance:
0/Cholesterol, HDL; 0/Fatty Acids; 57-88-5/Cholesterol

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