Document Detail

A serum melatonin rhythm in chickens and its abolition by pinealectomy.
MedLine Citation:
PMID:  1078656     Owner:  NLM     Status:  MEDLINE    
Melatonin, a suspected hormone of the pineal organ, was extracted from chicken serum and quantified by the Rana pipiens bioassay. When chickens were housed in an alternating light-dark photoperiod, serum melatonin was usually not detected during the light phase. Serum melatonin rose within 1 hr after the lights were extinguished, plateaued around midnight and fell before the lights were turned on. Serum melatonin was not detected at any time of day in pinealectomized chickens, suggesting that the pineal is neccessary for, and may be the source of, circulating melatonin.
R W Pelham
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Endocrinology     Volume:  96     ISSN:  0013-7227     ISO Abbreviation:  Endocrinology     Publication Date:  1975 Feb 
Date Detail:
Created Date:  1975-05-06     Completed Date:  1975-05-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375040     Medline TA:  Endocrinology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  543-6     Citation Subset:  AIM; IM    
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MeSH Terms
Biological Assay
Circadian Rhythm
Melatonin / blood*
Pineal Gland / physiology*
Rana pipiens
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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