Document Detail


The sequence-specific nuclear matrix binding factor F6 is a chicken GATA-like protein.
MedLine Citation:
PMID:  8492798     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The sequence-specific DNA-binding protein factor F6, which binds upstream of the cluster of the chicken alpha-globin genes, has previously been found to interact with a DNA fragment containing a replication origin and a nuclear matrix binding site. This protein has been partially characterized. Based on its molecular weight and binding affinity, F6 belongs to a family of GATA proteins, the chicken equivalent of transcription factor NFE-1. An oligonucleotide including the binding site for F6 competes for binding of the above-mentioned DNA fragment to the nuclear matrix. This indicates an involvement of this protein in the interaction between DNA and the nuclear matrix.
Authors:
Y S Vassetzky; C V De Moura Gallo; A N Bogdanova; S V Razin; K Scherrer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Molecular & general genetics : MGG     Volume:  238     ISSN:  0026-8925     ISO Abbreviation:  Mol. Gen. Genet.     Publication Date:  1993 Apr 
Date Detail:
Created Date:  1993-06-17     Completed Date:  1993-06-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0125036     Medline TA:  Mol Gen Genet     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  309-14     Citation Subset:  IM    
Affiliation:
Institut Jacques Monod, Paris, France.
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MeSH Terms
Descriptor/Qualifier:
Animals
Antigens, Nuclear
Base Sequence
Cell Line, Transformed
Chickens
DNA-Binding Proteins / drug effects,  isolation & purification,  physiology*
Distamycins / pharmacology
Erythroid-Specific DNA-Binding Factors
GATA1 Transcription Factor
Molecular Sequence Data
Nuclear Matrix / chemistry*
Nuclear Proteins / drug effects,  isolation & purification,  physiology*
Regulatory Sequences, Nucleic Acid
Transcription Factors
Chemical
Reg. No./Substance:
0/Antigens, Nuclear; 0/DNA-Binding Proteins; 0/Distamycins; 0/Erythroid-Specific DNA-Binding Factors; 0/GATA1 Transcription Factor; 0/Nuclear Proteins; 0/Transcription Factors; 636-47-5/stallimycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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