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A sensitive method for the detection of catecholamine based on fluorescence quenching of CdSe nanocrystals.
MedLine Citation:
PMID:  18970268     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A sensitive method for the detection of catecholamine based on the fluorescence quenching of CdSe nanocrystals was developed. The sodium citrate-protected CdSe nanocrystals were synthesized in water solution. The fluorescence quenching of CdSe nanocrystals by dopamine, uric acid, ascorbic acid and catechol was studied; the results showed that all of these four kinds of compounds could quench the fluorescence of nanocrystals, and the quenching constant was 6.3x10(4), 2.57x10(3), 2.14x10(3) and 1.168x10(3), respectively. The order of sensitivity for the biosensor was: dopamine>lactic acid>ascorbic acid>catechol. This method shows good selectivity for dopamine, the detection limit reaches 5.8x10(-8)M.
Authors:
Ying Ma; Cheng Yang; Nan Li; Xiurong Yang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Talanta     Volume:  67     ISSN:  1873-3573     ISO Abbreviation:  Talanta     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2008-10-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984816R     Medline TA:  Talanta     Country:  England    
Other Details:
Languages:  eng     Pagination:  979-83     Citation Subset:  -    
Affiliation:
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
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