Document Detail

A semipermeable skin dressing for extremely low birth weight infants.
MedLine Citation:
PMID:  8869535     Owner:  NLM     Status:  MEDLINE    
Skin breakdown and high fluid requirements are common problems in extremely low birth weight infants that may be reduced by application of a semipermeable skin dressing (SPD). An SPD was applied to 39 study infants who weighed < 1000 gm (control subjects, n = 37) to determine whether it would protect the skin and decrease fluid requirements. Randomization occurred before 12 hours of life and SPD was applied to the chest, abdomen, and back. Sixty-one infants survived the first 14 days. Skin remained nonerythematous, intact, and undamaged under the dressing, whereas uncovered skin sustained significant breakdown in both groups. No significant differences were found in fluid or electrolyte status. Although the SPD did not affect fluid requirements, the significant improvement in skin integrity under the SPD may justify its use in premature infants with delicate skin.
M L Donahue; D L Phelps; S E Richter; J M Davis
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  16     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:    1996 Jan-Feb
Date Detail:
Created Date:  1997-01-03     Completed Date:  1997-01-03     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  20-6     Citation Subset:  IM    
Department of Pediatrics, Medical University of South Carolina, Charleston 29425-3313, USA.
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MeSH Terms
Infant Mortality
Infant, Low Birth Weight*
Infant, Newborn
Isotonic Solutions
Membranes, Artificial*
Plasma Substitutes / administration & dosage,  therapeutic use
Rehydration Solutions / administration & dosage,  therapeutic use
Skin Diseases / prevention & control*
Skin Physiological Phenomena
Survival Analysis
Grant Support
Reg. No./Substance:
0/Isotonic Solutions; 0/Membranes, Artificial; 0/Plasma Substitutes; 0/Rehydration Solutions; 0/crystalloid solutions

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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