Document Detail


The selectivity of the anorectic effect of satietin. I. The ineffectiveness of satietin on behavioral tests.
MedLine Citation:
PMID:  7167418     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Satietin, a potent endogenous anorectic substance separated from human serum, plays a role of a rate limiting satiety signal in the negative feed back of food intake. The selectivity of satietin on some behavioral tests (unconditioned avoidance reaction, one-way as well as two-way conditioning, open field, consolidated conditioned reflex) was checked and compared to calcitonin. TRH and Glp-Leu-Pro-OH. Satietin seemed to be ineffective on all but one (open field) behavioral tests. Calcitonin and Glp-Leu-Pro-OH increased open field activity. Results indicate that satietin is an endogenous anorectic substance with a peculiar selectivity.
Authors:
B Knoll; J Knoll
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Polish journal of pharmacology and pharmacy     Volume:  34     ISSN:  0301-0244     ISO Abbreviation:  Pol J Pharmacol Pharm     Publication Date:  1982  
Date Detail:
Created Date:  1983-05-05     Completed Date:  1983-05-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0366561     Medline TA:  Pol J Pharmacol Pharm     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  17-23     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Appetite Depressants / pharmacology*
Avoidance Learning / drug effects
Behavior, Animal / drug effects*
Calcitonin / pharmacology*
Conditioning, Operant / drug effects
Female
Glycopeptides / pharmacology*
Male
Motor Activity / drug effects
Rats
Rats, Inbred Strains
Time Factors
Chemical
Reg. No./Substance:
0/Appetite Depressants; 0/Glycopeptides; 72026-83-6/satietin; 9007-12-9/Calcitonin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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