Document Detail

The sedative and analgesic effects of detomidine (Domosedan) in donkeys.
MedLine Citation:
PMID:  8578910     Owner:  NLM     Status:  MEDLINE    
Detomidine (Domosedan) was administered to four groups of donkeys, using four different dosages (5, 10, 20 and 40 micrograms/kg bwt) intravenously. The drug provided adequate sedation at dosages of 5 and 10 micrograms/kg bwt. Sedation deepened only slightly by increasing the dose. Analgesia was considered good with a dose of 20 micrograms/kg, and 40 micrograms/kg provided a deep analgesia associated with a longer duration. No significant changes had been observed in haematocrit (PCV), haemoglobin content (Hb %), total red and white cell counts and differential leucocytic counts. It was concluded that detomidine is a valuable sedative and analgesic drug to be used in donkeys without any serious implications.
M B Mostafa; K A Farag; E Zomor; M M Bashandy
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Zentralblatt für Veterinärmedizin. Reihe A     Volume:  42     ISSN:  0514-7158     ISO Abbreviation:  Zentralbl Veterinarmed A     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1996-03-14     Completed Date:  1996-03-14     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0331323     Medline TA:  Zentralbl Veterinarmed A     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  351-6     Citation Subset:  IM    
Department of Veterinary Surgery, Anaesthesiology and Radiology, Faculty of Veterinary Medicine, Cairo University, Egypt.
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MeSH Terms
Analgesics / administration & dosage,  pharmacology*
Blood Cell Count / drug effects,  veterinary
Dose-Response Relationship, Drug
Equidae / blood,  physiology*
Heart Rate / drug effects
Hypnotics and Sedatives / administration & dosage,  pharmacology*
Imidazoles / administration & dosage,  pharmacology*
Injections, Intravenous / veterinary
Reg. No./Substance:
0/Analgesics; 0/Hypnotics and Sedatives; 0/Imidazoles; 76631-46-4/detomidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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