Document Detail


The secretion signal of YopN, a regulatory protein of the Yersinia enterocolitica type III secretion pathway.
MedLine Citation:
PMID:  15342604     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The type III secretion signal of Yersinia enterocolitica YopN was mapped using a gene fusion approach. yopN codons 1 to 12 were identified as critical for signal function. Several synonymous mutations that abolish secretion of hybrid proteins without altering the codon specificity of yopN mRNA were identified.
Authors:
John W Goss; Joseph A Sorg; Kumaran S Ramamurthi; Hung Ton-That; Olaf Schneewind
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of bacteriology     Volume:  186     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-02     Completed Date:  2004-09-29     Revised Date:  2014-11-12    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  6320-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Artificial Gene Fusion
Bacterial Proteins / genetics*
Biological Transport
DNA Mutational Analysis
Genes, Bacterial
Genes, Reporter
Kanamycin Kinase / genetics,  metabolism
Membrane Proteins / genetics*
Protein Sorting Signals / genetics*
Yersinia enterocolitica / genetics*,  pathogenicity
Grant Support
ID/Acronym/Agency:
AI42797/AI/NIAID NIH HHS; T32 GM007183/GM/NIGMS NIH HHS; T32GM007183/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Bacterial Proteins; 0/Membrane Proteins; 0/Protein Sorting Signals; 138341-76-1/YopN protein, Yersinia; EC 2.7.1.95/Kanamycin Kinase
Comments/Corrections

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