Document Detail


Is screening of TORCH worthwhile in women with bad obstetric history: an observation from eastern Nepal.
MedLine Citation:
PMID:  21528793     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This pilot case-control study at a tertiary-care hospital over a four-month period was aimed at evaluating the possible usefulness of screening of TORCH (Toxoplasma gondii, rubella virus, cytomegalovirus, and Herpes simplex virus) in females with bad obstetric history. The study included 12 women with bad obstetric history and a similar number of matched controls with previous normal pregnancies. A serological evaluation of TORCH infections was carried out by detecting IgG and IgM antibodies against these infections by ELISA test-kit. Statistical analysis was not done to compare the results relating to the two groups due to a small number of cases and controls included in the study. Ten (83.3%) of the 12 cases with bad obstetric history and two (16.7%) of the 12 healthy controls were serologically positive at least for one of the TORCH agents. The seropositivity rate in women with bad obstetric history was quite high compared to that in the normal healthy controls. The results suggest that a previous history of pregnancy wastage and the serological evaluation of TORCH infections during current pregnancy must be considered while managing cases with bad obstetric history.
Authors:
Namrata Kumari; Norman Morris; Renu Dutta
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of health, population, and nutrition     Volume:  29     ISSN:  1606-0997     ISO Abbreviation:  J Health Popul Nutr     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-05-02     Completed Date:  2011-05-24     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  100959228     Medline TA:  J Health Popul Nutr     Country:  Bangladesh    
Other Details:
Languages:  eng     Pagination:  77-80     Citation Subset:  IM    
Affiliation:
Department of Microbiology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India. irainrai@yahoo.co.in
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Case-Control Studies
Cytomegalovirus Infections / blood,  diagnosis,  epidemiology*
Enzyme-Linked Immunosorbent Assay
Female
Herpes Simplex / blood,  epidemiology*
Humans
Immunoglobulin G / blood
Immunoglobulin M / blood
Mass Screening / methods*,  utilization*
Nepal / epidemiology
Pilot Projects
Pregnancy
Pregnancy Complications / epidemiology*
Pregnancy Complications, Infectious / blood,  diagnosis,  epidemiology
Pregnancy Outcome / epidemiology
Rubella / blood,  diagnosis,  epidemiology*
Serologic Tests
Toxoplasmosis / blood,  epidemiology*
Young Adult
Chemical
Reg. No./Substance:
0/Immunoglobulin G; 0/Immunoglobulin M
Comments/Corrections

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