Document Detail

The scleroderma Assessment Questionnaire (SAQ). A new self-assessment questionnaire for evaluation of disease status in patients with systemic sclerosis.
MedLine Citation:
PMID:  16501926     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To develop a self-assessment questionnaire and estimate its validity in the evaluation of disease status in patients with systemic sclerosis. PATIENTS AND METHODS: The developed questionnaire (SAQ) consists of 23 questions divided into four groups related to symptoms of vascular, respiratory, gastrointestinal and musculoskeletal dysfunction. One hundred and five patients with systemic sclerosis filled in the SAQ. Answers were assessed on a 0-3 scale and Index of Vascular Status (IVS), Index of Respiratory Status (IRS), Index of Gastrointestinal Status (IGS), Index of Musculoskeletal Status (IMMS) and Index of Disease Status (IDS) were calculated. Mann-Whitney and Kruskal-Wallis tests were used to examine the correlation of index score for particular organ system with various disease damage indicators. RESULTS: Mean score for IVS was significantly higher in patients with finger-tip ulcers or finger-tip osteolysis than in patients without, and was also higher in patients who had more severe capillary damage. Mean score for IRS was significantly higher in patients with pulmonary fibrosis, also in patients with reduced FVC, DLCO and DLCO/VA. Patients with esophageal hypomotility had a higher mean score for IGS than patients with normal esophageal motility. The mean score for IMSS showed a strong correlation with the skin score and was significantly higher in patients with reduced hand motility, joint contractures, muscle weakness or arthralgia/arthritis. The mean score for IDS was significantly higher in patients who had multisystemic involvement. CONCLUSIONS: The Scleroderma Assessment Questionnaire (SAQ) is a sensitive measurement of disease status and level of impairment of different organ systems in patients with systemic sclerosis.
P Ostojić; N Damjanov
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Zeitschrift für Rheumatologie     Volume:  65     ISSN:  0340-1855     ISO Abbreviation:  Z Rheumatol     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2007-04-30     Completed Date:  2007-05-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0414162     Medline TA:  Z Rheumatol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  168-75     Citation Subset:  IM    
Institute of Rheumatology, School of Medicine, University of Belgrade. ostojic@net.yu
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MeSH Terms
Middle Aged
Pain Measurement / methods*
Reproducibility of Results
Scleroderma, Systemic / classification,  diagnosis*
Self-Examination / methods*
Sensitivity and Specificity
Severity of Illness Index*

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