Document Detail

A safe strategy to decrease fetal lead exposure in a woman with chronic intoxication.
MedLine Citation:
PMID:  20459344     Owner:  NLM     Status:  MEDLINE    
During pregnancy skeletal lead is mobilized by maternal bone turnover and can threaten fetal development. The exact strategy suggested to women of childbearing age, who were chronically exposed to lead, and, thus, have high bone lead burden, is not well established. We describe 4 years of follow-up of a 29-year-old woman with chronic lead intoxication. We (a) advised her to delay conception until 'toxicological clearance', (b) treated her with multiple courses of lead chelator, DMSA, and (c) prescribed oral calcium. Patient had low blood lead and protoporphyrin level during pregnancy until delivery. Delaying conception, lead chelation, and calcium supplementation can decrease fetal exposure.
Adi Leiba; Howard Hu; Amin Zheng; Stefanos N Kales
Related Documents :
7171494 - Results of heavy drinking in pregnancy.
1872354 - The three most common occupational exposures reported by pregnant women: an update.
14637264 - A new modified gamma-%cdt method improves the detection of problem drinking: studies in...
2592904 - Confounding variables in studying the effects of maternal alcohol consumption before an...
22902204 - Novel human polyomaviruses in pregnancy: higher prevalence of bkpyv, but no wupyv, kipy...
25236644 - Maternal near-miss case reviews: the uk approach.
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  23     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-16     Completed Date:  2010-11-04     Revised Date:  2014-05-08    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  932-4     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Calcium / therapeutic use
Chelating Agents / therapeutic use*
Fetal Diseases / prevention & control*
Lead Poisoning / drug therapy*,  prevention & control
Prenatal Exposure Delayed Effects / prevention & control*
Succimer / therapeutic use*
Grant Support
R01 ES005257/ES/NIEHS NIH HHS; R01-05257//PHS HHS; R01-07821//PHS HHS
Reg. No./Substance:
0/Chelating Agents; DX1U2629QE/Succimer; SY7Q814VUP/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comment and reply on: Neonatal asphyxia and forensic medicine.
Next Document:  Studying the non-uniform expansion of a stent influenced by the balloon.