Document Detail


A rule-based seizure prediction method for focal neocortical epilepsy.
MedLine Citation:
PMID:  22361267     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: In the present study, we have developed a novel patient-specific rule-based seizure prediction system for focal neocortical epilepsy.
METHODS: Five univariate measures including correlation dimension, correlation entropy, noise level, Lempel-Ziv complexity, and largest Lyapunov exponent as well as one bivariate measure, nonlinear interdependence, were extracted from non-overlapping 10-s segments of intracranial electroencephalogram (iEEG) data recorded using electrodes implanted deep in the brain and/or placed on the cortical surface. The spatio-temporal information was then integrated by using rules established based on patient-specific changes observed in the period prior to a seizure sample for each patient. The system was tested on 316 h of iEEG data containing 49 seizures recorded in 11 patients with medically intractable focal neocortical epilepsy.
RESULTS: For seizure occurrence periods of 30 and 50 min our method showed an average sensitivity of 79.9% and 90.2% with an average false prediction rate of 0.17 and 0.11/h, respectively. In terms of sensitivity and false prediction rate, the system showed superiority to random and periodical predictors.
CONCLUSIONS: The nonlinear analysis of iEEG in the period prior to seizures revealed patient-specific spatio-temporal changes that were significantly different from those observed within baselines in the majority of the seizures analyzed in this study.
SIGNIFICANCE: The present results suggest that the patient specific rule-based approach may become a potentially useful approach for predicting seizures prior to onset.
Authors:
Ardalan Aarabi; Bin He
Related Documents :
12780947 - The role of transbronchial needle aspiration in the diagnosis of bronchogenic carcinoma.
17476617 - Proposal to decrease the number of negative temporal artery biopsies.
20630827 - Computed tomography-guided percutaneous needle biopsy of indeterminate pulmonary pathol...
17050957 - Management of the minimally abnormal papanicolaou smear in pregnancy.
18075417 - The clinical value of tc-99m trodat-1 spect for evaluating disease severity in young pa...
2301257 - Lack of correlation between transient myocardial ischemia and late potentials on the si...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2012-02-22
Journal Detail:
Title:  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology     Volume:  123     ISSN:  1872-8952     ISO Abbreviation:  Clin Neurophysiol     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-28     Completed Date:  2012-07-30     Revised Date:  2014-09-15    
Medline Journal Info:
Nlm Unique ID:  100883319     Medline TA:  Clin Neurophysiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1111-22     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Electroencephalography / methods*
Epilepsies, Partial / physiopathology*
Female
Humans
Male
Neocortex / physiopathology*
Seizures / physiopathology*
Grant Support
ID/Acronym/Agency:
EB006433/EB/NIBIB NIH HHS; EB007920/EB/NIBIB NIH HHS; R01 EB006433/EB/NIBIB NIH HHS; R01 EB006433-03/EB/NIBIB NIH HHS; R01 EB007920/EB/NIBIB NIH HHS; R01 EB007920-04/EB/NIBIB NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Comparison of coherence and phase synchronization of the human sleep electroencephalogram.
Next Document:  Sjogren's syndrome: An update on clinical, basic and diagnostic therapeutic aspects.