| rt-PA thrombolysis in acute thromboembolic upper-extremity arterial occlusion. | |
| | |
MedLine Citation:
|
PMID: 11779009 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: Retrospective analysis of the results of rt-PA thrombolysis in the treatment of acute thromboembolic occlusion of the upper limb. METHODS: Of 55 patients with demonstrated acute embolic arterial occlusion, rt-PA thrombolysis was performed on 40 occlusions in 38 patients (23 women with a mean age of 62 years, range 32-85 years; 15 men with a mean age of 65 years, range 32-92 years) according to the following design: 6 mg rt-PA/hr for 30 min, 3 mg rt-PA/hr for the next 30 min, 1 mg rt-PA/hr for 7 hr, and 0.4 mg rt-PA/hr until the end of lysis. Onset of symptoms varied from 1 to 14 days. Included were three isolated upper-arm occlusions, nine combined brachial and forearm occlusions, and 28 forearm and hand artery occlusions. RESULTS: The overall success rate was 55%. The lysis results for isolated upper arm, combined brachial and forearm occlusions, and forearm and hand artery occlusions were 100%, 66%, and 46%, respectively. In eight patients surgical embolectomy had to be performed after failed thrombolysis. No amputation was required in the follow-up period. No lethal complications occurred. CONCLUSIONS: Interventional rt-PA treatment of proximal upper-extremity arterial occlusions may be performed with comparable success rates to surgical embolectomy and without severe complications. For distal occlusions the results are inferior to the success rates obtained with surgery. |
| | |
Authors:
|
M Cejna; E Salomonowitz; H Wohlschlager; K Zwrtek; R Böck; R Zwrtek |
Related Documents
:
|
9763249 - Arterial reconstruction in the ischemic hand and wrist: effects on microvascular physio... 8269489 - Glidewire treatment of resistant coronary occlusions. 750079 - Transmural triglycerides in acute myocardial ischaemia. 1244689 - Isotope angiograpy for detection of embolic arterial occlusion. 9336499 - Extradural aneurysms. 2742289 - Idiopathic bilateral branch-artery occlusion in a young woman. 2687719 - Spontaneous dissection of both extracranial internal carotid arteries. 10147579 - Coronary angioscopy: a monorail angioscope with movable guide wire. 22182759 - A malignant case of acute promyelocytic leukemia with occlusion of carotid artery by tu... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Cardiovascular and interventional radiology Volume: 24 ISSN: 0174-1551 ISO Abbreviation: Cardiovasc Intervent Radiol Publication Date: 2001 Jul-Aug |
Date Detail:
|
Created Date: 2002-01-07 Completed Date: 2002-02-07 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8003538 Medline TA: Cardiovasc Intervent Radiol Country: United States |
Other Details:
|
Languages: eng Pagination: 218-23 Citation Subset: IM |
Affiliation:
|
Department of Radiology, Hospital St. Pölten, Austria. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acute Disease Adult Aged Aged, 80 and over Arm / blood supply* Brachial Artery / radiography Embolectomy Female Humans Male Middle Aged Recombinant Proteins / therapeutic use Retrospective Studies Thromboembolism / drug therapy*, etiology, radiography, surgery Thrombolytic Therapy* Tissue Plasminogen Activator / therapeutic use* |
| Chemical | |
Reg. No./Substance:
|
0/Recombinant Proteins; EC 3.4.21.68/Tissue Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Square stent: a new self-expandable endoluminal device and its applications.
Next Document: Complications of percutaneous nephrostomy, percutaneous insertion of ureteral endoprosthesis, and re...