Document Detail

Is routine urine cytology useful in the haematuria clinic?
MedLine Citation:
PMID:  18325219     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: The objective of this study was to determine the value of routine urine cytology in the initial evaluation of patients presenting to a one-stop haematuria clinic. PATIENTS AND METHODS: A total of 1000 consecutive patients who attended the haematuria clinic between June 2003 and November 2004 were studied prospectively. A standard protocol was used to investigate these patients. This included urine cytology, upper tract imaging and flexible cystoscopy. RESULTS: Overall, 986 samples of urine were sent for cytology. In 126 patients, the report was abnormal; of these, 71 patients were found to have bladder transitional cell carcinoma by flexible cystoscopy and a further 3 had upper tract transitional cell carcinoma diagnosed radiologically. The remaining 52 patients with abnormal cytology were not found to have cancer on further investigations. The total cost for urine cytology and additional investigations was pound50,535. CONCLUSIONS: In this study of the initial evaluation of patients with haematuria, no case of urothelial malignancy was diagnosed on the basis of urine cytology alone. Therefore, urine cytology need not be used routinely in the initial diagnostic work-up for haematuria.
S Viswanath; B Zelhof; E Ho; K Sethia; R Mills
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of the Royal College of Surgeons of England     Volume:  90     ISSN:  1478-7083     ISO Abbreviation:  Ann R Coll Surg Engl     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-07     Completed Date:  2008-04-21     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7506860     Medline TA:  Ann R Coll Surg Engl     Country:  England    
Other Details:
Languages:  eng     Pagination:  153-5     Citation Subset:  IM    
Department of Urology, Norfolk and Norwich University Hospital NHS Trust, Norwich, UK.
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MeSH Terms
Aged, 80 and over
Ambulatory Care / economics
Carcinoma, Transitional Cell / diagnosis*
Cost-Benefit Analysis
Diagnostic Tests, Routine / economics
Hematuria / diagnosis*,  economics,  urine
Middle Aged
Prospective Studies
Urinary Bladder Neoplasms / diagnosis
Urine / cytology*
Urologic Neoplasms / radiography*

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