Document Detail


The roles of excessive gastro-oesophageal reflux, disordered oesophageal motility and decreased mucosal sensitivity in the pathogenesis of Barrett's oesophagus.
MedLine Citation:
PMID:  9187887     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Barrett's oesophagus is often considered an end stage of gastro-oesophageal reflux disease. In its pathogenesis increased oesophageal acid exposure, disturbed oesophageal motility and decreased oesophageal mucosal sensitivity are thought to be of importance. In this review the role of each of these factors will be discussed and an update of the recent literature will be given.
Authors:
E C Niemantsverdriet; R Timmer; R Breumelhof; A J Smout
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European journal of gastroenterology & hepatology     Volume:  9     ISSN:  0954-691X     ISO Abbreviation:  Eur J Gastroenterol Hepatol     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-08-04     Completed Date:  1997-08-04     Revised Date:  2009-10-16    
Medline Journal Info:
Nlm Unique ID:  9000874     Medline TA:  Eur J Gastroenterol Hepatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  515-9     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology, St Antonius Hospital, Nieuwegein, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Animals
Barrett Esophagus / etiology*,  metabolism,  physiopathology
Esophageal Motility Disorders / complications,  metabolism,  physiopathology
Gastric Acid / secretion*
Gastroesophageal Reflux / complications*,  metabolism,  physiopathology
Humans
Hydrogen-Ion Concentration
Intestinal Mucosa / metabolism*,  pathology
Manometry

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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