Document Detail

The role of venous return in critical illness and shock-part I: physiology.
MedLine Citation:
PMID:  23269130     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To provide a conceptual and clinical review of the physiology of the venous system as it is relates to cardiac function in health and disease.
DATA: An integration of venous and cardiac physiology under normal conditions, critical illness, and resuscitation.
SUMMARY: The usual teaching of cardiac physiology focuses on left ventricular function. As a result of the wide array of shock states with which intensivists contend, an approach that takes into account the function of the venous system and its interaction with the right and left heart may be more useful. This two-part review focuses on the function of the venous system and right heart under normal and stressed conditions. The first part describes the basic physiology of the venous system, and part two focuses on the role of the venous system in different pathophysiologic states, particularly shock.
CONCLUSION: An improved understanding of the role of the venous system in health and disease will allow intensivists to better appreciate the complex circulatory physiology of shock and may allow for better hemodynamic management of this disorder.
Duane J Funk; Eric Jacobsohn; Anand Kumar
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Critical care medicine     Volume:  41     ISSN:  1530-0293     ISO Abbreviation:  Crit. Care Med.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-27     Completed Date:  2013-03-04     Revised Date:  2013-10-09    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  255-62     Citation Subset:  AIM; IM    
Section of Critical Care Medicine, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
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MeSH Terms
Cardiac Output
Coronary Circulation*
Critical Illness*
Fluid Therapy / methods
Heart Function Tests*
Shock / physiopathology*,  therapy
Vasoconstrictor Agents / pharmacology,  therapeutic use
Vasodilator Agents / pharmacology,  therapeutic use
Venous Pressure
Ventricular Dysfunction, Right / diagnosis,  physiopathology*
Reg. No./Substance:
0/Vasoconstrictor Agents; 0/Vasodilator Agents
Comment In:
Crit Care Med. 2013 Sep;41(9):e237-9   [PMID:  23979389 ]
Crit Care Med. 2013 Sep;41(9):e239   [PMID:  23979390 ]

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