Document Detail

The role of vasopressin in the management of sepsis.
MedLine Citation:
PMID:  22585336     Owner:  NLM     Status:  In-Data-Review    
With mortality rates approaching 40%, septic shock is one of the most common causes of death on intensive care units. Vasodilatation, myocardial depression and fluid loss as a result of increased capillary permeability result in hypotension and impaired organ perfusion. Multiple organ failure as a consequence of organ hypo-perfusion results in death. Initial therapeutic strategies involve fluid resuscitation and pharmacological means to increase mean arterial pressure. The catecholamines dopamine, noradrenaline and adrenaline are the predominant pharmacological agents used.
Justin C Roberts; Leanne M Darwin; Stephen Washington
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of hospital medicine (London, England : 2005)     Volume:  73     ISSN:  1750-8460     ISO Abbreviation:  Br J Hosp Med (Lond)     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-05-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101257109     Medline TA:  Br J Hosp Med (Lond)     Country:  England    
Other Details:
Languages:  eng     Pagination:  298-Unknown     Citation Subset:  IM    
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