Document Detail


The role of vascular failure in coronary artery spasm.
MedLine Citation:
PMID:  21067896     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Coronary artery spasm plays an important role in the pathogenesis of angina pectoris as well as acute coronary syndrome and sudden death. The prevalence of coronary spasm is greater in East Asian populations than in other parts of the world. Although the mechanism of coronary spasm is still unclear, both endothelial and smooth muscle dysfunction have been reported to play a role. We recently proposed a new concept termed 'vascular failure' that represents an integration of endothelial and smooth muscle abnormalities. Thus, vascular failure is the primary cause of coronary artery spasm.
Authors:
Hiroaki Kawano; Koichi Node
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Publication Detail:
Type:  Journal Article     Date:  2010-11-09
Journal Detail:
Title:  Journal of cardiology     Volume:  57     ISSN:  1876-4738     ISO Abbreviation:  J Cardiol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804703     Medline TA:  J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  2-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Department of Cardiovascular & Renal Disease Medicine, Saga University, Saga City, Japan. koumei@cc.saga-u.ac.jp
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