| The role of suppression in amblyopia. | |
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MedLine Citation:
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PMID: 21447685 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Aim. This study had three main aims; to assess the degree of suppression in patients with strabismic, anisometropic and mixed amblyopia, to establish the relationship between suppression and the degree of amblyopia and to compare the degree of suppression across the clinical sub-groups within our sample. Methods. Using both standard measures of suppression (Bagolini lenses and ND filters, Worth 4 dots) and a new approach involving the measurement of dichoptic motion thresholds under conditions of variable interocular contrast, we quantified the degree of suppression in 43 amblyopic patients with strabismus, anisometropia or a combination of both. Results. There was good agreement between the quantitative measures of suppression made using the new dichoptic motion threshold technique and measurements made using standard clinical techniques (Bagolini lenses and ND filters, Worth 4 dots). The degree of suppression was found to directly correlate with the degree of amblyopia within our clinical sample whereby stronger suppression was associated with a greater interocular acuity difference and poorer stereoacuity. Suppression was not related to the type or angle of strabismus when this was present or the previous treatment history. Conclusions. These results suggest that suppression may have a primary role in the amblyopia syndrome and therefore have implications for the treatment of amblyopia. |
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Authors:
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Jingrong Li; Benjamin Thompson; Carly S Y Lam; Daming Deng; Lily Y L Chan; Goro Maehara; George C Woo; Minbin Yu; Robert F Hess |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-3-29 |
Journal Detail:
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Title: Investigative ophthalmology & visual science Volume: - ISSN: 1552-5783 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-3-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7703701 Medline TA: Invest Ophthalmol Vis Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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